SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination medrxivpreprint EmoryUniversity SARSCoV2 COVID19 StrokeRisk PostVaccination
By Tarun Sai LomteFeb 13 2023Reviewed by Aimee Molineux In a recent study posted to medRxiv* preprint server, researchers examined the factors associated with stroke following coronavirus disease 2019 vaccination.
The study and findings In the present study, researchers assessed the association of baseline factors, SARS-CoV-2 infection, and vaccine type with early onset of stroke after the first COVID-19 vaccine dose. They included all adults from Georgia, United States , vaccinated from December 2020 to February 2022. Demographic and vaccination data were sourced from the Georgia Registry of Immunization Transactions and Services database.
Most subjects were females and White . Of these, around 9% had a history of COVID-19 before vaccination, and 0.4% were infected during the 21-day interval. Most participants received Pfizer’s BNT162b2 , followed by Moderna’s mRNA-1273 and Ad26.COV2.S . The incidence of ischemic stroke within 21 days post-vaccination was 11.14, 8.14, and 10.4 per 100,000 individuals, respectively, for mRNA-1273, BNT162b2, and Ad26.COV2.S recipients.