Scientists Develop Malaria Vaccine With 'World-Changing' Potential

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Scientists Develop Malaria Vaccine With 'World-Changing' Potential
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'We really could be looking at a very substantial reduction in that horrendous burden of malaria,' said JennerInstitute director Adrian Hill.

, Hill"has previously said he believes R21 could help to reduce deaths from the disease by 70% by 2030 and eradicate it by 2040."It has taken more than a century to develop effective vaccines as the malaria parasite, which is spread by mosquitoes, is spectacularly complex and elusive. It is a constantly moving target, shifting forms inside the body, which make it hard to immunize against.for the first vaccine—developed by pharmaceutical giant GSK—to be used in Africa.

Results from a randomized controlled trial involving 409 children aged 5-17 months in Nanoro, Burkina Faso—showed that three initial doses of the R21 vaccine before the malaria season, followed by a booster dose one year later, provides protective efficacy up to 80%.the results"another encouraging signal that, with the right support, the world could end child deaths from malaria in our lifetimes.

The Serum Institute of India, the world's largest vaccine manufacturer, is prepared to produce at least 200 million doses of R21 annually.Hill,"we really could be looking at a very substantial reduction in that horrendous burden of malaria."

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