Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature - Acta Neuropathologica Communications

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Severe CTE and TDP-43 pathology in a former professional soccer player with dementia: a clinicopathological case report and review of the literature - Acta Neuropathologica Communications
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A Case Report in Acta Neuropathologica Communications presents a case of a former professional Dutch soccer player with young-onset dementia and pathology-confirmed CTE, thus increasing awareness about the correlation between soccer and neurodegeneration.

The patient has provided written consent to use his clinical data and biomaterial for future research purposes, as part of the Amsterdam Dementia Cohort, which was approved by the Medical Ethics Committee of the VU medical center under the reference number 2016/061. Before death, the patient’s next of kin gave written informed consent for brain donation to the NEwTON cohort of the Netherlands Brain Bank , according to the ethical guidelines of brain banking.

has received consultancy fees from Biogen, Brainstorm Therapeutics, ImmunoBrain Checkpoint, New Amsterdam Pharma, ReMynd and Treeway, Vivoryon, and Vigil Neuroscience. He is the PI of studies with ACImmune, CogRx, Green Valley, IONIS, Janssen, Roche, Rodin Therapeutics, Sanofi, UCB, and Vivoryon. is the Editor-in-Chief of Acta Neuropathologica Communications.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This file includes a detailed description of the immunostaining methods and the search queries for the literature search.This article is licensed under a Creative Commons Attribution 4.

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