Author Sir Salman Rushdie has been stabbed at least once in the neck and once in the abdomen while on stage at an event in New York state
Rushdie's legs were raised. Pic: AP
A video posted online showed a number of people rushing on stage in the aftermath as Sir Salman was tended to. They added:"The interviewer suffered a minor head injury. A state trooper assigned to the event immediately took the suspect into custody. The Chautauqua County Sheriff's Office assisted at the scene."
In 1998, Iran's pro-reform government of President Mohammad Khatami distanced itself from the fatwa, saying the threat against Rushdie was over after he had lived in hiding for nine years. His first three novels - Grimus , Midnight's Children and Shame - were all met with praise but it was his fourth - The Satanic Verses - that brought criticism.
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1029 genomes of self-declared healthy individuals from India reveal prevalent and clinically relevant cardiac ion channelopathy variants - Human GenomicsBackground The prevalence and genetic spectrum of cardiac channelopathies exhibit population-specific differences. We aimed to understand the spectrum of cardiac channelopathy-associated variations in India, which is characterised by a genetically diverse population and is largely understudied in the context of these disorders. Results We utilised the IndiGenomes dataset comprising 1029 whole genomes from self-declared healthy individuals as a template to filter variants in 36 genes known to cause cardiac channelopathies. Our analysis revealed 186,782 variants, of which we filtered 470 variants that were identified as possibly pathogenic (440 nonsynonymous, 30 high-confidence predicted loss of function ). About 26% (124 out of 470) of these variants were unique to the Indian population as they were not reported in the global population datasets and published literature. Classification of 470 variants by ACMG/AMP guidelines unveiled 13 pathogenic/likely pathogenic (P/LP) variants mapping to 19 out of the 1029 individuals. Further query of 53 probands in an independent cohort of cardiac channelopathy, using exome sequencing, revealed the presence of 3 out of the 13 P/LP variants. The identification of p.G179Sfs*62, p.R823W and c.420 + 2 T | C variants in KCNQ1, KCNH2 and CASQ2 genes, respectively, validate the significance of the P/LP variants in the context of clinical applicability as well as for large-scale population analysis. Conclusion A compendium of ACMG/AMP classified cardiac channelopathy variants in 1029 self-declared healthy Indian population was created. A conservative genotypic prevalence was estimated to be 0.9–1.8% which poses a huge public health burden for a country with large population size like India. In the majority of cases, these disorders are manageable and the risk of sudden cardiac death can be alleviated by appropriate lifestyle modifications as well as treatment regimens/clinical interventions. Clinical utility of the obtained variants was
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Salman Rushdie stabbed in the neck while on stage at an event in New York StateNew York State police said: “Rushdie suffered an apparent stab wound to the neck and was transported by helicopter to an area hospital. His condition is not yet known.”
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Police identify suspect after Salman Rushdie stabbed in the neck and abdomen while on stage at New York eventPolice have identified the suspect behind an attack on author Sir Salman Rushdie, who was airlifted to hospital after being stabbed in the neck and abdomen ahead of an event in upstate New York.
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