Noninvasive modulation of brain hemodynamic and metabolic states by near-infraredlight SPIEtweets
which demonstrated a solution by utilizing a multi-channel setup along with principle component analysis. Finally, this study investigated the effects of tPBM with limited wavelengths on one lateral forehead and only one wavelength on both lateral foreheads. The conclusions given in the study need to be further confirmed as a generalized finding.
As for future work, advances of the 2-bbNIRS system are needed to minimize the head movement, sleepiness effects, and contaminations from extracranial layers. Also, to be able to select an optimal wavelength and stimulation site for tPBM intervention, concurrent measurements and correlations between behavioral and neurophysiological alterations induced by tPBM would be beneficial for a specific neurological application.
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