Smart drugs fall short as cognitive function enhancers SmartDrugs Cognitive ProductivityDecrease MotivationBoost ProblemSolving SmartPills TaskPerformance QualityOfEffort MentalPerformance ScienceAdvances
By Dr. Priyom Bose, Ph.D.Jun 18 2023 Recently, there has been an increase in the use of stimulant prescription-only drugs by students and employees to increase their academic and other work productivity. Even though it has been perceived that these drugs enhance an individual’s cognitive functions, the available evidence is inconclusive. Typically, improvements in cognitive capacities have only been found in the clinical population instead of the general public.
MPH and DEX are catecholaminergic agonists which are associated with the enhancement of dopaminergic activity in cortical and subcortical areas. They also exhibit norepinephrine activity. However, MPH is an inhibitor of the dopamine and norepinephrine transporter. Here, participants were randomly assigned into four groups. Following a counterbalanced Latin square design, each group was provided with a different sequence of medications and PLC across sessions. During the knapsack task, each participant was presented with several items, which were associated with weight and value.
Interestingly, if an individual under PLC exhibited a significant increase in knapsack value per move, the same person tended to be below average under smart drugs. Similarly, for an individual who performed below average under PLC, the quality of effort was above average under smart drugs. This reversal in effort quality could be because participants were found to be more erratic in their choices under smart drugs.
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