The drug, called lecanemab, reduced the rate of cognitive decline by 27% in a study of nearly 1,800 people in the early stages of Alzheimer's, scientists reported at the Clinical Trials on Alzheimer's Disease meeting in San Francisco.
People who got infusions of lecanemab scored about half a point better on a zero-to-18-point scale of mental functioning, a slight but statistically significant difference., who directs the Yale Alzheimer's Disease Research Center and presented an overview of the study at the meeting.of the National Institute on Aging, who was not involved in the study, called the results"a very small effect.
Thambisetty emphasized that his views are his own, and that he is not speaking for the NIA, which is part of the National Institutes of Health. of the Barrow Neurological Institute, who gave a presentation on lecanemab's safety. And the number of abnormalities detected on brain scans was"within expectations," he says.
That drug, also developed by Eisai and Biogen, was approved in 2021 despite conflicting evidence about whether it worked, and after an FDA advisory committee voted against approval.
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