Synthetic 'forever chemical' linked to liver cancer

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Synthetic 'forever chemical' linked to liver cancer
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Synthetic 'forever chemical' linked to livercancer KeckSchool_USC

Exposure to a synthetic chemical found widely in the environment is linked to non-viral hepatocellular carcinoma, the most common type of liver cancer, according to a new study conducted by researchers from the Keck School of Medicine of USC and published inThe chemical, called perfluooctane sulfate or PFOS, is one of a class of man-made chemicals called per- and polyfluoroalkyl substances, or PFAS.

"This builds on the existing research, but takes it one step further," said Jesse Goodrich, Ph.D., a postdoctoral scholar in the Department of Population and Public Health Sciences at the Keck School of Medicine."Liver cancer is one of the most serious endpoints in liver disease and this is the first study in humans to show that PFAS are associated with this disease.

"Part of the reason there has been few human studies is because you need the right samples," said Veronica Wendy Setiawan, Ph.D., professor of population and public health sciences at the Keck School of Medicine."When you are looking at an environmental exposure, you need samples from well before a diagnosis because it takes time for cancer to develop."

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