Combining machine learning with explainable artificial intelligence (XAI) to predict biological age with personalized explanations.
By Pooja Toshniwal PahariaNov 9 2023Reviewed by Lily Ramsey, LLM In a recent study published in The Lancet Healthy Longevity, researchers introduced a computational ExplaiNAble BioLogical Age estimation framework combining machine learning with explainable artificial intelligence to predict biological age with personalized explanations.
Studies have concentrated on first-generation biological age clocks aimed at predicting chronological age. These clocks have fewer connections with mortality risk than second-generation clocks, and their relationships with other aging outcomes are varied. Enhanced XAI techniques were used to derive the Shapley additive explanations values and determine the extent to which the input features contributed to ENABL Age estimation.
Features missing in most samples, highly correlated features, and individuals who died due to external reasons were excluded. ENABL Age attained high mortality estimation power, as indicated by the area under the receiver operating characteristic curve values of 0.8 for five- and ten-year mortality among UKBB participants and 0.9 for the corresponding mortality estimations among NHANES participants.
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Autism brain states may hold the key to unlocking childhood memoriesNeuroscientists have discovered a fascinating connection between the retention of early life memories and brain developmental trajectories associated with autism.
Read more »
Repay your existing mortgage by unlocking the money tied up in your home...3.3 million UK homeowners aged 55 and over currently have outstanding mortgages. For these homeowners who are looking to reduce their committed monthly expenditure by repaying their existing mortga…
Read more »
A new connection between the gut microbiota and prostate inflammation in aging menA new research paper titled 'Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids' has been published in Aging.
Read more »
Deciphering reproductive aging in women using a NOD/SCID mouse modelA new research paper titled 'Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes has been published in Aging.
Read more »
Organisers offer update on Pat Jennings statue unveiling eventNorthern Ireland football legend Pat Jennings collapsed and was taken to hospital before Monday night's Tottenham vs Chelsea game
Read more »
Santini Aldo Bib TightsSupremely comfortable bib tights that offer good insulation and breathability, and some rain resistance
Read more »