We found a genetic link between routine bloodtest results and mentalhealthdisorders ConversationEDU ScienceAdvances
Many studies have tried to address this by focusing on substances called biomarkers that can be readily measured in blood.
Biomarkers found in routine blood tests are useful as they are often affected by diet and lifestyle, or by treatment with a drug.It's often difficult to study the role of these blood biomarkers in mental health conditions. Many studies in this area are often not large enough to make strong conclusions.
The widespread availability of genetic data has allowed us to investigate how huge numbers of tiny changes in the DNA sequence are related to the risk of mental illness. These same variants can then also be linked to the measured levels of a biomarker in blood. To take one example, there was a positive genetic correlation in our study between white blood cell count and depression. This could indicate some process in our body influences both depression and white blood cells.
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