For many people with treatment-resistant depression, in recent years hope has been offered by psychedelics such as psilocybin, the key active ingredient in magic mushrooms. It appears that psychedelics may 'flip the switch' on rigid brain networks,
behind this latest study, to understand whether psilocybin may help to alleviate depression and anxiety, and how psychedelic drugs affect the brain more generally.
as taking a common antidepressant, escitalopram – a drug that often comes with impactful side effects of weight gain, lack of libido, and insomnia.But observing positive benefits among small groups of people is one thing; untangling what's happening in the brain is another challenge altogether – and so far, the mechanisms of how psilocybin works in the brain have remained poorly understood.
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