What is the correlation between specific COVID-19 clinical characteristics and anti-SARS-CoV-2 antibody titers? researchsquare Hujimed COVID19 SARSCoV2 AntibodyTiters ClinicalCharacteristics
By Tarun Sai LomteNov 3 2022Reviewed by Aimee Molineux In a recent study posted to Research Square* preprint server, researchers investigated the associations between clinical characteristics of coronavirus disease 2019 and immunoglobulin G antibodies against severe acute respiratory syndrome coronavirus 2 .
The study and findings In the current study, researchers evaluated the correlations between anti-SARS-CoV-2 IgG and clinical features of COVID-19 in a heterogeneous population comprising students, staff, and their household members. Blood samples were collected from the students and staff members of Hebrew Gymnasium in December 2020. Moreover, samples were obtained from their household members.
Myalgia and fever were less common in students during acute COVID-19 than in other study groups. Other acute and residual symptoms were comparable among participants. Anti-SARS-CoV-2 IgG antibodies were detected in 120 PCR-positive subjects seven months after testing SARS-CoV-2-positive, implying 80% sensitivity of the serologic test.
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