World's First Transient Pacemaker 1 Step Closer to Clinical Use

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World's First Transient Pacemaker 1 Step Closer to Clinical Use
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A wireless cardiac pacemaker — one that breaks down and dissolves inside the body after its job is complete — would reduce the potentially fatal risk of heart tissue damage that comes with extraction of implanted pacemakers.

their idea, but this latest research builds on that earlier work, adding wearable sensors that would be used to monitor the device.Called a transient pacemaker, the wireless device can be implanted in patients who need temporary pacing after cardiac surgery or who are awaiting a permanent pacemaker. Once its job is done, the pacemaker"harmlessly" dissolves inside the body, releasing an anti-inflammatory drug to prevent"foreign-body reactions," according to a press statement.

Using algorithms, it picks up on any abnormal cardiac rhythms and helps pace the heart. Meanwhile, physicians can remotely monitor a patient using a smartphone or tablet. When the sensors detect a low battery or a pacemaker malfunction, they can address the issue immediately, contacting the patient to come in if necessary. The patient is not tasked with self-monitoring, Rogers added.

Transient devices are also likely to advance work in tissue engineering, science investigating ways to restore and replace injured or damaged tissue — in burn patients, for example."They can serve as the backbone of engineered tissue transplants to patients," said Efimov,"monitoring transplants until they fully integrate with the host organ."

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