In a BugBitten blog post, SciAnouk discusses a study on a promising vaccine candidate for toxoplasmosis to protect highly susceptible squirrel monkeys in parks and zoos.
By I, Luc Viatour, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=2136833Monkeys are very susceptible to Toxoplasma gondii infections, and for squirrel monkeys toxoplasmosis is often fatal. The reason for this seems to be linked to the evolution of New World Primates and the lack of co-evolution with T. gondii.
Currently there is only one commercially available vaccine that protects from toxoplasmosis. This vaccine protects sheep and helps prevent aborted foetuses. However, this is a live attenuated vaccine which is not suitable to highly susceptible species such as squirrel monkeys. Vaccines and Tests Before vaccination, all monkeys were tested for T. gondii antibodies using the High Sensitivity Direct Agglutination test. Five were found to be seropositive for T. gondii and were not vaccinated, to act as positive controls. In total forty-eight squirrel monkeys housed across six French Zoos were vaccinated.
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