Changes in mortality associated with temperature-sensitive diseases in Japan during the COVID-19 pandemic PLOSONE COVID19 coronavirus covid disease temperature Japan mortality
By Bhavana KunkalikarOct 14 2022Reviewed by Danielle Ellis, B.Sc. In a recent study published in PLOS ONE, researchers assessed the impact of the coronavirus disease 2019 pandemic on temperature-sensitive disease mortality.
The three largest cities that were the focus of this study were Sapporo City , Osaka City , and Tokyo 23 wards , which have a population of 1.97 million, 2.75 million, and 9.71 million, respectively, in 2021. These teams were assessed because they exhibited different climates. For example, in August, the mean ambient temperatures were 22.3 °C in Sapporo, 29 °C in Osaka, and 26.9 °C in Tokyo, while the mean temperatures in December were 0.9 °C in Sapporo, 17.
Related StoriesFurthermore, the duration of the COVID-19 pandemic was considered to be from March to December 2020, and the months between 2010 and 2019 were compared with those in the pre-pandemic era.
Ireland Latest News, Ireland Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism - Molecular MedicineBackground Long-COVID is characterized by prolonged, diffuse symptoms months after acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking. We investigated vascular transformation biomarkers in Long-COVID patients. Methods A case–control study utilizing Long-COVID patients, one to six months (median 98.5 days) post-infection, with multiplex immunoassay measurement of sixteen blood biomarkers of vascular transformation, including ANG-1, P-SEL, MMP-1, VE-Cad, Syn-1, Endoglin, PECAM-1, VEGF-A, ICAM-1, VLA-4, E-SEL, thrombomodulin, VEGF-R2, VEGF-R3, VCAM-1 and VEGF-D. Results Fourteen vasculature transformation blood biomarkers were significantly elevated in Long-COVID outpatients, versus acutely ill COVID-19 inpatients and healthy controls subjects (P | 0.05). A unique two biomarker profile consisting of ANG-1/P-SEL was developed with machine learning, providing a classification accuracy for Long-COVID status of 96%. Individually, ANG-1 and P-SEL had excellent sensitivity and specificity for Long-COVID status (AUC = 1.00, P | 0.0001; validated in a secondary cohort). Specific to Long-COVID, ANG-1 levels were associated with female sex and a lack of disease interventions at follow-up (P | 0.05). Conclusions Long-COVID patients suffer prolonged, diffuse symptoms and poorer health. Vascular transformation blood biomarkers were significantly elevated in Long-COVID, with angiogenesis markers (ANG-1/P-SEL) providing classification accuracy of 96%. Vascular transformation blood biomarkers hold potential for diagnostics, and modulators of angiogenesis may have therapeutic efficacy.
Read more »
Associations of cardioprotective medications with COVID-19 outcomesAssociations of cardioprotective medications with COVID-19 outcomes PLOSONE BrighamWomens HarvardChanSPH harvardmed COVID19 coronavirus covid cardioprotective medication
Read more »
COVID-19 cases in UK rocket by almost a third in weekData released by the Office for National Statistics shows in the week ending 3 October the number of people testing positive for coronavirus stood at 1.7 million, up 31% from 1.3 million previously - the biggest hike since June.
Read more »
COVID-19 vaccination reduced the severity of the Omicron-driven pandemic wave in Saudi ArabiaIn a new study, researchers conducted a retrospective study of all COVID-19 cases from a single hospital in the Kingdom of Saudi Arabia (KSA) between December 25, 2021, and February 30, 2022.
Read more »
Chinese study determines the real-world effectiveness of COVID-19 vaccinesChinese study determines the real-world effectiveness of COVID-19 vaccines FrontiersIn FrontImmunol COVID19 coronavirus covid vaccine vaccination
Read more »