Devastating heart condition can be reversed, study shows for the first time uclnews nejm
Lead author Professor Marianna Fontana said,"We have seen for the first time that the heart can get better with this disease. That has not been known until now and it raises the bar for what might be possible with new treatments."
Senior author Professor Julian Gillmore , Head of the UCL Centre for Amyloidosis, based at the Royal Free Hospital, said,"Whether these antibodies caused the patients' recovery is not conclusively proven. However, our data indicates that this is highly likely and there is potential for such antibodies to be recreated in a lab and used as a therapy. We are currently investigating this further, although this research remains at a preliminary stage."called transthyretin .
The imaging techniques also mean the burden of amyloid on the heart, and consequently the progression of the disease, can be more precisely monitored, making it easier to detect cases where the condition has reversed, rather than merely remaining stable.
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