Does obstructive sleep apnea increase the risk of post-acute sequelae of SARS-CoV-2? SleepApnea COVID19 LongTermEffects PASC ObstructiveSleepApnea HealthResearch SleepDisorders PostCOVID ResearchSleep
By Neha MathurMay 15 2023 In a recent article published in the journal Sleep, researchers generated a harmonized analysis investigating the impact of preexisting obstructive sleep apnea as a risk factor for post-acute sequelae of severe acute respiratory syndrome coronavirus 2 [PASC] in children and adults. They used electronic health record data from three research networks within the REsearching COVID to Enhance Recovery initiative funded by the National Institutes of Health .
PASC risk varies by gender, age, and specific preexisting health conditions like hypertension and diabetes, raising the possibility that OSA could be a risk factor for PASC. Nevertheless, studies have barely investigated and elucidated the impact of preexisting conditions like OSA on the risk of developing PASC. In addition, studies should look beyond acute outcomes among COVID-19 survivors having preexisting comorbid OSA.
A clinical science core at New York University Langone Health coordinated all three RECOVER research networks, albeit each network created distinct diagnosis-based computable phenotype definitions to find probable PASC patients on its own. Notably, algorithms designed to identify patients with an OSA diagnosis from EHRs have excellent validity.
Related StoriesLastly, the researchers used logistic regression models to estimate unadjusted and adjusted odds ratios with 95% confidence intervals for the association between a preexisting OSA diagnosis and the likelihood of developing PASC.
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