DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)

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DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)
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Researchers find a way to help slow the next epidemic statuses cellpressnews

). This database summarized antiviral activities and developmental status of approved, investigational and experimental 120 BSAs which inhibit 86 human viruses, belonging to 25 viral families. It was mostly used for drug repurposing/repositioning, the main approach in the search for new indications for available antivirals against emerging and re-emerging viruses, and became a popular tool among academic and clinical virologists, pharmacologists, and students.

Here, we present an integrative DrugVirus.info 2.0 portal for exploration and analysis of BSAs and BCCs. The updated data portal contains a comprehensive database that significantly expands the number of BSAs and incorporates BCC data. The interactive modules provide a variety of data analysis tools, including the possibility to analyze user-provided BSAs and BCCs, compare them with internal databases, and interactively explore BSAs’ structure–activity relationship.

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