Epigenetic dysregulation from chromosomal transit in micronuclei - Nature

Research finds unexpected link between chromosomalinstability and epigeneticalterations sloan_kettering nature

Intra-clone variability and change in accessibility

We computed the mean and variance of log-transformed signal fold changes for each chromosome in a single clone to understand the global changes in accessibility . To control for high fold changes caused by error in windows with low read counts, windows in which neither the clone nor the parent has more than 200 reads were excluded from this calculation.

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