Keto diet as a PCOS treatment Diet WomensHealth PolycysticOvarySyndrome Ovaries PCOS Keto Diet WeightLoss SpringerNature unipegaso_it MyUniSR SapienzaRoma
By Dr. Liji Thomas, MDJan 29 2023Reviewed by Benedette Cuffari, M.Sc. Reproductive function is vital to human survival and well-being. Thus, the incidence of polycystic ovarian syndrome in women, often associated with infertility, has received considerable attention among researchers.
PCOS is also linked to multiple metabolic disorders, including glucose intolerance, type 2 diabetes mellitus, hyperinsulinism, insulin resistance, hypertension, and fatty liver. In addition, an earlier report suggested a link between PCOS and excessive dietary carbohydrate intake, leading to insulin resistance and hyperandrogenism. Obesity is also more prevalent among women with PCOS.
In the VLCKD, fats provide 90% of calories, with carbohydrates and proteins providing the remaining 10%. This diet is adopted in three stages, beginning with the active stage, followed by the re-education and maintenance phases. The VLCKD has been shown to support rapid weight loss while maintaining lean mass, thus preserving glucose metabolism throughout the process.What did the study show? Research shows that body composition and carbohydrate metabolism are involved in PCOS.
Other dietary interventions tested in this area include the low GI diet, which might reduce inflammation in PCOS through increased glutathione peroxidase activity, a potent antioxidant molecule. Additionally, the pulse-based diet, which provides high-quality proteins, complex carbohydrates, and increased fiber, has resulted in better ovarian morphology and reduced androgen levels.
KD causes weight loss and reduces fat mass, both of which reduce insulin secretion after meals, restoring insulin sensitivity and improving glucose tolerance. In PCOS, KD can reduce androgen levels and normalize the ratio of luteinizing hormone to follicle-stimulating hormone . However, more studies are needed to determine the impact of the KD over time.
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