Luke O'Neill: Compound in magic mushrooms has a 'big effect' on depression | Newstalk

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Luke O'Neill: Compound in magic mushrooms has a 'big effect' on depression | Newstalk
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“A third of people responded very well - people with severe depression who didn’t respond to any other therapy.'

A psychedelic compound found in magic mushrooms has been found to have a “big effect” on people suffering from severe depression, Professor Luke O’Neill has said.

A clinical trial gave people 1mg, 10mg or 25mg of psilocybin - followed by therapy sessions - and the results found that many responded positively to the treatment. “There was always evidence that things like magic mushrooms… could help people with depression,” Professor O’Neill told“It was always questioned and now a trial has been done with psilocybin mushrooms and, low and behold, [there’s a] big effect on severe depression.“So, it’s causing big excitement.”Globally, an estimated 100 million people have treatment resistant depression and around half of them are so ill they cannot perform basic household tasks.

Prof Guy Goodwin, the chief medical officer of the company that ran the trial, said the results were “a very satisfactory outcome.” A further trial, which will test the impact of two doses of psilocybin, will begin later on next year.

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