A lorry, a van and two cars were involved in the crash near junction 22.
The slip road heading on to the M1 at junction 23 southbound, near Shepshed, was closedEmergency services were called at about 08:50 BST to the crash on the southbound side between junctions 23 and 22, near the exit slip road for Markfield.National Highways said it was a serious collision, initially causing traffic delays of up to six miles.
The northbound carriageway between junctions 22 and 23 was also closed to allow the air ambulance to land but has since reopened. National Highways said diversions have been put into place, adding congestion has been reduced to about three miles.
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