Map of how our brain changes with age could help diagnose diseases

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Map of how our brain changes with age could help diagnose diseases
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Similar to paediatric growth charts, having a reference for standard brain growth changes could help medics diagnose neurological conditions earlier in their onset.

changes throughout our life could aid the diagnosis of neurological conditions.

“It’s the first time that anyone sort of stitched together these developmental patterns really, throughout the whole lifespan, going from even pre-birth to old age,” saysBethlehem and his colleagues analysed 123,984 MRI scans from 101,457 humans, from a 16.5-week fetus to 100 year olds, from more than 100 studies.

The average thickness of the cortex, the brain’s outer region, peaked at 1.7 years old. Cortex thinning has been linked with neurological conditions such asRead more:“If there are effects of this feature later in life as a function of disease, and [cortical thickness] peaks really early, then that poses the interesting question of should we be studying what leads to these diseases starting from really early on?” says Seidlitz.

The brain map could one day act as a reference for standard brain growth, similar to paediatric growth charts, helping clinicians and researchers better track the onset of neurological conditions. “I am excited to learn about this colossal first step towards generating brain development charts that will in the future facilitate more accurate and early diagnosis of atypical developmental patterns [and neurodegenerative conditions],” saysIn the meantime, the brain scans of a more diverse population need be studied.

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