Mitochondria power supply failure may cause age-related cognitive impairment salkinstitute
, these pieces can get lost or altered, and no longer fit in the greater brain puzzle. A research team has now published a study in"Fifty percent of people experience loss of working memory with old age, meaning their ability to hold and manipulate information in the short-term decreases," says co-first author Courtney Glavis-Bloom, a senior staff scientist in Salk Institute Professor John Reynolds's lab.
, and behavior," says Glavis-Bloom."Investigating these microscopic dysfunctions is uncharted territory that could revolutionize our understanding of aging and its impact on cognition." The team found that adherence to the ultrastructural size principle was essential for avoiding working memory impairment with age. By viewing violation of the ultrastructural size principle and-related failures as the key to age-related cognitive impairment, the study ushers in a new era for aging research.
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