New Insights into Dynamic Imaging Use of Magnetic Nanoparticles AdvSciNews nanomedicine
By Bhavna KavetiSep 20 2022Reviewed by Susha Cheriyedath, M.Sc. Unlike non-magnetic nanomaterials, multifunctional magnetic nanoparticles have unique properties, including degradability, remote motion controllability, and diagnostic imaging. Multifunctional magnetic nanoparticles are remotely controllable via magnetic fields and have the advantages of biocompatibility and high tissue-penetrability.
Additionally, the difficulties in implementing magnetic dynamic imaging and therapy in clinical settings have been explored. The imaging capacity of multifunctional magnetic nanoparticles during dynamic magneto-cell regulation allows for safe, noninvasive, localized, and on-demand regulation for state-of-the-art cancer and regenerative therapy.
Consequently, multifunctional magnetic nanoparticles are utilized in various research fields owing to their high magnetic susceptibility, superparamagnetism, and inductive magnetic moment, controlled by an external magnetic field. The iron-based composition of magnetic nanoparticles produces chemical ferroptotic signals and enables imaging-guided targeted therapy, whereas the motion controllability of magnetic nanoparticles exerts magnetic-mechanical signals or generates heat energy. These distinct benefits of multifunctional magnetic nanoparticles have made it possible to modify the cell microenvironment in situ for the regeneration of various tissues, along with immunoengineering, which still has scope for improvement.
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