Population-based cohort study of oral contraceptive use and risk of depression | Epidemiology and Psychiatric Sciences | Cambridge Core

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Population-based cohort study of oral contraceptive use and risk of depression | Epidemiology and Psychiatric Sciences | Cambridge Core
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New study links contraceptive pills and depression UU_University

In the time-dependent analysis, continued use of OCs was not associated with an increased rate of depression . However, both recent and previous OC users had an increased hazard of depression , respectively, compared with never users. The increased hazard of depression in previous users was driven by adolescent OC users , whereas no significant association was found for adult OC users 2 years after discontinuing .

**Parous women were followed until 1 year before delivery.Sensitivity analysis on the subcohort of women who self-identified as white did not yield any marked changes to the risk estimates . Similar estimates were also found when women with a medical indication for OC use and with other psychiatric disorders were excluded . In the sensitivity analysis where parous women were followed until 1 year before giving birth or depression , the HRs were slightly higher or similar .

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