Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients ERSpublications uhasselt airpollution pollution pollutants covid COVID19 SARSCoV2 hospitalization
By Neha MathurJun 23 2023Reviewed by Lily Ramsey, LLM In a recent study published in European Respiratory Journal, researchers investigated whether the accumulation of black carbon particles in the blood increased the risk of coronavirus disease 2019 severity, including a heightened risk for intensive care unit admission and prolonged hospitalization.
Furthermore, several studies using patient-level data have demonstrated associations between long-term air pollution and hospitalization risk, ICU admission risk, and mortality. Related StoriesThe team recorded their demographic and clinical characteristics and information on education and occupation. They used their blood and urine samples for biochemical and hematological measurements, including C-reactive protein and absolute white blood cell count . The primary clinical study outcomes were the duration of hospitalization and the need for ICU admission.
The authors noted that for these individuals, even minimal improvements in air quality resulted in health gains of 40 to 80% from novel COVID-19 therapies, e.g.,remdesivir drug therapy. Patient gender also modified the association between short-term PM2.5 exposure and the duration of hospitalization, with the effect being more pronounced in men than women, most likely because underlying comorbidities are more prevalent in men than women, albeit other biological factors might also be involved.
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