Study reveals alarming pediatric antibiotic prescribing practices in Madagascar, Senegal, and Cambodia Antibiotics Pediatrics GlobalHealth ChildrensHealth LMICs AntibioticResistance PublicHealth HealthcareChallenges PLOSMedicine
Additionally, they robustly documented disease symptoms and diagnoses in these children while evaluating antibiotic needs during each consultation.
First, the researchers calculated the main characteristics of the study population in each country, including the number of consultations, diagnoses, antibiotic prescriptions, and inappropriate antibiotic prescriptions. Further, they used chi2 or exact Fisher tests to compare countries on qualitative and quantitative variables, with the significance threshold of all bilateral tests set at 0.05.
Related StoriesFurther, the study results suggested that inappropriate antibiotic prescribing is frequent but highly heterogeneous across countries. Accordingly, while only 16% of consultations not requiring antibiotics resulted in antibiotic prescriptions in Senegal, the figures for Cambodia were much higher, i.e., ~57%.
The most prescribed antibiotic to young children in Madagascar and Cambodia was amoxicillin, which doctors prescribed in 24% and 35.7% of consultations, respectively, and cefixime in Senegal, prescribed in 34.4% of all children consultations. The choice of antibiotics was comparable in Cambodia and Madagascar relative to Senegal.
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